DogsBite.org, a research organization dedicated to educating the public on severe and fatal dog attacks in the U.S., acting as an advocate for bite victims, and reducing serious dog attacks, collected data over a 16-year period from 2005-2020 to find the seven dog breeds responsible for the most fatal attacks on humans. Read on to discover the deadliest dog breeds in the U.S. RELATED: This Is the Most Aggressive Dog Breed, New Study Says. Fatal attacks from 2005 to 2020: 14 RELATED: This Is the Most Dog-Friendly U.S. City in 2021, Data Shows. Fatal attacks from 2005 to 2020: 18 Fatal attacks from 2005 to 2020: 20 Fatal attacks from 2005 to 2020: 24ae0fcc31ae342fd3a1346ebb1f342fcb And for more useful information sent straight to your inbox, sign up for our daily newsletter.  Fatal attacks from 2005 to 2020: 29 Fatal attacks from 2005 to 2020: 51 Fatal attacks from 2005 to 2020: 380 RELATED: This Is the Deadliest Animal in the U.S., According to Data.